Phosphofructokinase deficiency is the entry on the Springer's list that most owners have never heard of, and it is the one with the cleanest answer.
It is an inherited enzyme deficiency that leaves red blood cells fragile under stress. Affected dogs can have episodes of dark red or brown urine, weakness, fever and pale gums after hard exercise, excitement or heavy panting in heat — which is to say, after exactly the situations a 5/5 exercise spaniel is in constantly.
There is a DNA test, and no good reason for a breeder not to have used it. Ask for the result by name.
Hip and elbow dysplasia and progressive retinal atrophy complete the list, with hip scores as numbers and eye certification the corresponding asks.
The Malamute's own DNA-testable condition is inherited polyneuropathy, which shows in young dogs as exercise intolerance, a wobbly or high-stepping gait and a change to the bark. Its list also carries hip and elbow dysplasia, hypothyroidism, hereditary cataracts, progressive retinal atrophy, epilepsy, heart disease, bloat and zinc-responsive skin disease.
Only the Malamute carries a real bloat risk, and that household should know the signs.