It is unusual for the giant breed to be the longer-lived one, and here it is: 10 to 14 years for the Malamute against 10 to 12 for the Golden. The reason is on the Golden's health list, which is the longest of any breed on this site.
Cancer sits near the top of that list and it is the honest headline of Golden Retriever ownership. The breed carries a well-documented predisposition to haemangiosarcoma and lymphoma in particular, and it is the reason the breed's life expectancy has not moved much despite it being one of the most popular and most carefully bred dogs in the world. Anyone choosing a Golden should go in knowing this, ask a breeder about longevity and cause of death in the line going back three generations, and treat any unexplained lethargy, pale gums or abdominal swelling in a middle-aged dog as an urgent appointment rather than a wait-and-see.
The rest of the Golden's list is long but more ordinary: hip and elbow dysplasia, heart disease, skin allergies, hypothyroidism, ear infections, obesity, cruciate ligament injuries, degenerative myelopathy and progressive retinal atrophy. Cruciate injuries deserve a mention because they are common, expensive, and strongly associated with letting a Golden get heavy.
The Malamute's list is shorter and shares the orthopaedic core — hip dysplasia, elbow dysplasia, hypothyroidism, epilepsy, bloat, progressive retinal atrophy — and adds three northern-breed specifics: zinc-responsive dermatosis, inherited polyneuropathy and hereditary cataracts.
Both are deep-chested and both list bloat, so split meals and a known route to an emergency clinic apply either way. On cost the Golden is slightly cheaper month to month at $120–250 against $150–300, but insurance quotes often narrow or reverse that gap because of the cancer history.