Addison's disease is the entry on the Poodle's list worth learning to recognise, because it is easy to miss and dangerous when missed.
The adrenal glands stop producing enough of the hormones that regulate salt, water and the stress response. The symptoms are vague and intermittent — lethargy, poor appetite, occasional vomiting or diarrhoea, weakness that comes and goes, often worse after a stressful event. It is sometimes called the great pretender for exactly that reason.
Untreated, it can produce an Addisonian crisis: sudden collapse with dangerous electrolyte changes, which is a genuine emergency. Diagnosed, it is managed well with hormone replacement and most dogs live normal lives.
A young adult Poodle with a repeating pattern of vague illness that resolves and returns deserves a specific test rather than another course of symptomatic treatment.
Hip dysplasia, progressive retinal atrophy, hypothyroidism, epilepsy, Cushing's disease, Legg-Perthes, ear infections, allergies and bloat complete the list.
The Akita's burden is autoimmune and endocrine too — immune-mediated disease, hypothyroidism, progressive retinal atrophy — with hip dysplasia and bloat.