Osteochondritis dissecans sits on the Rottweiler's list and it is a condition of growth rather than of age, which makes it one of the few entries an owner can genuinely influence.
OCD is a failure in the cartilage-to-bone conversion at a joint surface, usually the shoulder, elbow, knee or hock. A flap of cartilage separates and can break loose into the joint, producing lameness in a young dog — typically between four and ten months — that is often intermittent, worse after exercise, and easy to write off as a knock. Diagnosis is by imaging and treatment is frequently arthroscopic.
The risk factors are informative. Rapid growth, excess body weight during growth, over-supplementation with calcium, and high-impact exercise on a growing joint all increase the odds. That translates into concrete advice for a Rottweiler puppy: use a large-breed puppy food formulated with controlled calcium rather than an adult or all-life-stages food, do not supplement calcium at all, keep the puppy lean rather than chunky, and restrain forced exercise — no long walks, no stairs where avoidable, no repetitive jumping, no running alongside a bicycle — until growth plates close at around eighteen months. Free play on soft ground is the goal.
Hip and elbow dysplasia sit alongside it and share several of the same risk factors, which is why the same regime protects against all three. Ask any breeder for hip and elbow scores on both parents; a Rottweiler breeder who cannot produce them is not a serious one.
The rest of the list runs bloat, arthritis, hypothyroidism and progressive retinal atrophy. Bloat management is the standard set: split meals, quiet time either side of eating, a slow-feeder bowl if needed, and knowing where the out-of-hours clinic is.
The Malamute shares hip dysplasia, elbow dysplasia, bloat, hypothyroidism and progressive retinal atrophy, and adds hereditary cataracts, epilepsy, zinc-responsive dermatosis and inherited polyneuropathy.