The Bernedoodle's list is long: hip dysplasia, elbow dysplasia, progressive retinal atrophy, bloat, epilepsy, allergies, heart conditions, joint issues, skin conditions and Addison's disease.
Addison's is the one most worth recognising, because it hides. It is a failure of the adrenal glands to produce enough cortisol, it comes from the Poodle side, and its signs are vague and intermittent — episodes of lethargy, poor appetite, vomiting or diarrhoea, a dog that seems unwell and then seems fine. Untreated it can end in collapse. An ACTH stimulation test diagnoses it and lifelong medication manages it well. If a Bernedoodle has recurring unexplained illness, ask about adrenal testing specifically.
Bloat matters for the larger dogs in the range, given a Bernese-derived deep chest. Split meals, quiet time around eating, and a known out-of-hours route.
The screening questions for a litter are concrete: hip and elbow scores on both parents, progressive retinal atrophy DNA status on the Poodle side, cardiac examination, and honest information about longevity and cause of death in the Bernese lines behind the cross.
The Pit Bull's list runs hip and elbow dysplasia, skin allergies, heart murmurs, bloat, obesity, cruciate ligament disease, arthritis and cancer. Skin allergies are its most frequent day-to-day complaint — itching, chewed paws, recurrent ear trouble — and cruciate disease its most likely orthopaedic emergency, heavily driven by body weight.
Keeping either dog lean is the single most valuable habit available, and it is free.
On balance: the Bernedoodle asks for more money and more research, and gives back easier sociability and a possibly longer life. The Pit Bull asks for management and paperwork, and gives back predictability and the lowest running cost on this page.